Influenza viruses change from season to season and can even change within the course of one flu season updated guidance may be obtained at Uses: For the prophylaxis and treatment of signs and symptoms of infection caused by various strains of influenza A virus.Usual Geriatric Dose for Influenza Prophylaxis Use: For treatment of drug-induced extrapyramidal reactions. The extended-release capsules are not indicated for the treatment of drug-induced extrapyramidal reactions extended-release tablets are not interchangeable with other amantadine formulations see administration advise for additional administration information.Titration to 300 mg daily in divided doses may be beneficial in some patients.Immediate-release formulations: Initial dose: 100 mg orally twice a day Usual Adult Dose for Extrapyramidal Reaction Uses: For the treatment of dyskinesia in patients with Parkinson's disease the extended-release capsules are additionally indicated as adjunctive treatment to levodopa/carbidopa in patients with Parkinson's disease experiencing "off" episodes. This drug may be added to levodopa based therapy, with or without concomitant dopaminergic medications adding this drug to optimal well-tolerated doses of levodopa may smooth out fluctuations that can occur with levodopa alone patients reducing levodopa dose due to side effects may regain lost benefit with the addition of amantadine.For patients experiencing a falling-off effect after initial benefit with the immediate-release formulations, it may be beneficial to consider increasing the dose to 300 mg/day or temporarily interrupting therapy followed by re-initiation.Extended-release capsules and tablets are not interchangeable with each other or with other amantadine formulations see administration advise for additional administration information.May increase after 1 week to recommended dose of 274 mg orally once a day at bedtime.May increase in weekly intervals up to a maximum dose of 322 mg/dayĮxtended-release capsules: Initial dose: 137 mg orally once a day at bedtime.
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